We recommend consuming your MAG365BF within 48 hours as it gradually loses its high absorbability properties over time. If you consume your MAG365 BF immediately after activation, your stomach doesn’t need to break it down – it's already in a form your body can promptly use. If it's consumed after 48 hours, it remains a beneficial supplement with many health perks, but it will absorb similarly to non-ionic magnesium citrate, which boasts an approximately 30% absorbency rate (compared to the nearly 100% absorbency of ionic MAG365). For additional insights, refer to our article “Understanding Ionic".

Not necessarily. While vitamin C can begin to degrade slightly at temperatures above 85°F (29°C), significant breakdown typically doesn’t occur until temperatures exceed 140°F (60°C). Since boiling water is 212°F (100°C), using hot (but not boiling) water will keep most of the vitamin C intact.

MAG365 BF is designed to activate in water, and temperature simply affects how fast that happens:

• Hot water: activates in 30 seconds
• Warm water: activates in around 3 minutes
• Cold water: takes 20–30 minutes to fully activate

There’s less fizz with cold water, but you’ll know it’s ready when the mixture turns from cloudy to more translucent. So whether you choose hot, warm, or cold water, MAG365 BF will still work—just give it enough time to fully activate.

MAG365 BF+ Calcium features a 3:2 ratio of magnesium to calcium. Following comprehensive research on this topic, we consider this ratio ideal when factoring in dietary calcium intake. For more details, refer to the question “What is the relationship between calcium and magnesium?” below.

Magnesium and calcium work together to support muscle function, nerve signaling, bone health, and cardiovascular balance—but they must be properly balanced. While bones tend to benefit from a 2:1 calcium to magnesium ratio, the nervous system, muscles, and heart often require more magnesium relative to calcium.

Most modern diets are calcium-rich and magnesium-poor, which can lead to an imbalance that affects calcium absorption and increases the risk of calcium buildup in soft tissues. Magnesium is required to keep calcium in solution and guide it into the bones, rather than the joints or arteries.

Experts like Dr. Carolyn Dean (author of The Magnesium Miracle) recommend a ratio of around 1,000 mg calcium to 600 mg magnesium, while researcher Peter Gillham advocates for a 3:2 magnesium to calcium ratio in supplementation—particularly when the diet already provides ample calcium.

Importantly, excess calcium from supplements can deplete magnesium stores, while the body typically excretes excess magnesium through the stool, making it more forgiving. However, both minerals should be taken mindfully, ideally with supportive cofactors like vitamin D3, vitamin K2, vitamin C, and potassium to aid proper absorption and function.

For those who require extra calcium, our MAG365 BF + Calcium maintains a balanced 3:2 calcium to magnesium ratio and includes the cofactors needed for optimal absorption and bone health.

While calcium is widely known for supporting bone and dental health, research shows that calcium works best when combined with key cofactors like magnesium, vitamin D3, and vitamin K2. These nutrients help direct calcium to where it's needed—primarily the bones and teeth—and help prevent it from depositing in soft tissues.

Taking calcium without these cofactors may reduce its effectiveness and could contribute to unwanted calcium buildup in areas like the arteries or kidneys. That’s why proper balance and nutrient synergy are so important.

Most people get enough calcium from their diet, but it can be harder to get adequate magnesium, D3, and K2 through food alone. If you have low bone density or an existing bone health condition, we typically recommend our MAG365 BF + Calcium formula. It contains calcium in a 3:2 ratio with magnesium, along with supportive cofactors to aid proper absorption and utilization.

That said, it’s always a good idea to review your dietary intake and speak with your healthcare provider before starting or changing a supplement routine—especially for bone-related conditions.

We use vitamin D3 derived from lichen—a vegan-friendly organism formed from a symbiotic relationship between fungus and algae. Unlike most plant-based sources that only provide vitamin D2, lichen naturally produces cholecalciferol (vitamin D3), the same highly bioavailable form found in animal sources.

Traditional D3 sources like cod liver oil or lanolin (from sheep’s wool) aren’t vegan, and lanolin is often processed using harsh chemicals or pesticides—something we actively avoid. Lichen, on the other hand, is a clean, ethical source of vitamin D3 that aligns with our commitment to purity and vegan values.

Yes, it’s true—and it’s a detail many supplement companies overlook. Vitamin K2 is sensitive to alkaline minerals like magnesium and calcium. When combined without protection, K2 can begin to degrade during storage, significantly reducing its potency over time.

To prevent this, we use a double microencapsulated form of vitamin K2 (MK-7) in products like MAG365 BF, MAG365 Kids, Vitamin D Plus, and PrizMAG Plus. This protective technology helps preserve the stability and bioavailability of K2 from production through to consumption.

Without proper encapsulation, products combining K2 with magnesium or calcium may retain as little as 20% of their K2 content just one month after manufacturing. Breakdown rates vary depending on formulation and storage conditions, but stability is a critical factor when choosing a bone-support or multinutrient supplement.

MAG365 BF is not licensed for use during pregnancy. Please consult your healthcare provider before using any supplement while pregnant.

Nutrients like magnesium, vitamin D3, and other cofactors found in MAG365 BF are commonly studied for their general roles in muscle function, energy metabolism, and bone health—which are important during pregnancy. For pregnancy-specific supplementation, speak with your healthcare provider to find a product that meets your needs.

While MAG365 BF is not licensed specifically for hormonal regulation, it provides a powerful blend of nutrients that support many of the body’s systems impacted during key phases of a woman's life—especially PMS, perimenopause, and menopause.

  MAG365 BF helps to:

 
• Support energy metabolism and tissue formation, which may help ease fatigue, mood fluctuations, and brain fog often associated with PMS and the hormonal shifts of perimenopause.
 
• Maintain proper muscle function, including the heart muscle, which may contribute to relief from cramps, tension, and restlessness during the menstrual cycle and menopause transition.
 
• Support the development and maintenance of bones and teeth, a critical need as estrogen declines during and after menopause, increasing the risk of bone loss.
 
• Aid in the absorption and use of calcium and phosphorus, essential for long-term skeletal health and osteoporosis prevention.
 
• Support immune function, which can be helpful as immune resilience may fluctuate with age and stress levels.
 
• Provide electrolytes and support collagen formation for healthy skin, joints, and connective tissue—especially important as skin elasticity and joint comfort can decline with age.

  In addition to its strong nutritional profile, MAG365 BF has received   multiple awards for Best Women’s Health Product, and many customers report feeling more balanced and energized when using it consistently.

  As with any supplement, it's always best to speak with your healthcare provider to ensure it's the right fit for your individual needs.

It can be—but that’s not the only reason we created it. MAG365 BF was developed as one of the first calcium-free bone health formulas on the market. Why? Because recent research has raised concerns that excess calcium from supplements may contribute to calcium buildup in soft tissues like blood vessels and organs.

Since most people can get enough calcium through their diet, we focused instead on providing the cofactors your body needs to properly absorb and direct dietary calcium—such as magnesium, vitamin D3, vitamin C, potassium, and vitamin K2. These nutrients work together to support bone strength, calcium utilization, and overall mineral balance—without the risks associated with excess supplemental calcium.

MAG365 BF is ideal whether you’re already getting calcium from food or taking a separate calcium supplement—just be sure to talk to your healthcare provider to ensure your total intake is right for your needs.

When we originally named MAG365 BF, the “BF” stood for “Bone Formula.” It was developed to support bone health without including calcium—something that sets it apart in the market. While most bone supplements rely heavily on calcium, our research showed that many people already get sufficient calcium from their diets.

Instead, we focused on providing the often-overlooked cofactors needed to help the body properly use dietary calcium. These include key nutrients like magnesium, vitamin K2, vitamin D3, potassium, and vitamin C—nutrients that are harder to get in adequate amounts through diet alone but are essential for maintaining healthy bones and proper mineral balance.

While “Bone Formula” is the official meaning, many of our customers have given it affectionate nicknames like “Best Friend,” “Best Formula,” and even “Bear Formula”—a nod to how well many customers say it supports them through various wellness challenges. While MAG365 BF is not licensed as a hormone support supplement, it has received   multiple awards for Best Women’s Health Product, highlighting its popularity in that category.

The formulation of MAG365 BF was developed through extensive research to ensure the nutrients work synergistically for optimal absorption and effectiveness.

For example, vitamin D3 requires magnesium for activation, and vitamin K2 is essential for guiding calcium to the bones and teeth, rather than allowing it to accumulate in soft tissues like arteries or joints. These nutrients are carefully combined to support bone health and overall mineral balance.

To learn more about how the nutrients in MAG365 BF work together, check out our article on cofactors for healthy bones.

Magnesium is essential for the proper activation and function of vitamin D3 in the body. Without adequate magnesium, vitamin D3 remains in its inactive form and cannot carry out its role in calcium metabolism and immune support. In fact, every step of vitamin D metabolism—from synthesis to transport to activation—requires magnesium as a cofactor.

Vitamin K2 works synergistically with vitamin D3 by helping to direct calcium to the bones and teeth, where it's needed, and away from soft tissues like arteries and joints. While vitamin D3 enhances calcium absorption from the gut, vitamin K2 ensures that the absorbed calcium is properly utilized and doesn’t build up in the bloodstream.

Boron, another key ingredient in our MAG365 BF formula, also supports vitamin D3 metabolism by helping to extend its half-life and enhance its bioavailability.

For a deeper look into how these nutrients work together, read our full article on cofactors for healthy bones.

We use pyridoxal-5-phosphate (P5P), the active form of vitamin B6, in our MAG365 BF and MAG365 Kids formulas. Unlike pyridoxine (the common, inactive form), P5P doesn’t require conversion by the liver, making it more efficient and bioavailable—especially important for kids, individuals under stress, or anyone with impaired B6 metabolism. It directly supports neurotransmitter production, energy metabolism, and nervous system health in the form the body actually uses.