A Look Into What Makes MAG365 Unique
MAG365 is ITL Health’s Flagship Product
MAG365 is made up of only two ingredients: Magnesium Carbonate and Citric Acid. These ingredients, when combined with water, convert into ionic magnesium citrate. The addition of hot water causes the carbonate in the magnesium carbonate to disperse which causes the signature fizzing action of MAG365. The magnesium ion is then forced to bind to the citric acid, creating ionic magnesium citrate.
The term "ionic" can be hard to understand due to its multi-faceted nature. Read below to learn more about ionic magnesium citrate
MAG365 vs. Other Magnesium Citrate Powders
When you mix MAG365 in a glass of warm or hot water and allow it to finish fizzing, you will see the MAG365 appears translucent like water and looks as if nothing were added. (This also happens in cold water, but it takes longer. A natural result of the slower reaction is you will not see the fizzing action.)
However, if one then mixes another brand of magnesium citrate powder in a glass of water, there will be an obvious difference. There will be no “fizz” or activation process and the competing magnesium citrate powder will have settled on the bottom of the glass, often leaving the liquid murky and unblended.
Why is it that? Because MAG365 is in an ionic solution. There is a difference in the science between how MAG365 magnesium citrate behaves and how other magnesium citrate powders behave, and understanding the difference is where words like “ionic” and “salt” come in to play.
Defining Ionic
In chemistry, there are two main types of bonds; covalent and ionic. A covalent bond is formed between two non-metallic atoms, which is characterized by the sharing of pairs of electrons between atoms and other covalent bonds.1 An ionic bond is formed from an attraction between a positively and negatively charged ion, and is almost always formed between a metal and a non-metal.
By this elemental definition, all magnesium citrate is technically coupled together by an ionic bond,2 and one might assume that all magnesium citrate is “ionic.” That definition is correct if referring exclusively to the difference between covalent and ionic bonds.
Defining Organic
In chemistry, an organic compound is any chemical compound that contains carbon. By this definition, oil and gasoline are organic compounds.3
Equally, if someone were to say, "all foods are organic," they would be technically correct because all foods contain carbon compounds.
Defining Salt
According to the principles of chemistry, a salt is “a solid chemical compound consisting of an assembly of cations and anions.” Salts are composed of related numbers of cations (positively charged ions) and anions (negative ions) so that the product is electrically neutral (without a net charge).4 There are positive and negative ions; cations are positive and anions are negative. Table salt is a solid chemical compound consisting of Sodium cations (+) and Chlorine anions (-).
Magnesium citrate is also a salt, a solid chemical compound consisting of Magnesium cations (++) and Citrate anions (--). Both examples have “ionic” bonds because they have a metal (Sodium, Magnesium) and a non-metal (Chlorine, and Citrate).6 More specifically, magnesium citrate is a magnesium preparation in salt form with citric acid in a 3:2 ratio (three magnesium atoms per two citrate molecules).
MAG365 is a magnesium citrate with a 1:1 ratio, i.e. one Mg++ to one C7H6O7++. This ratio is much more absorbable than the common 3:2 ratio of magnesium citrate in salt form.
MAG365 is ionic because the molecules dissociate when the chemical reaction occurs.
MAG365 (unflavoured) is comprised of two ingredients; Magnesium Carbonate (MgCO3) and Citric Acid (C6H8O7). When you add it to water you get the chemical reaction MgCO3 + C6H8O7 --> C6H6MgO7 + H2O (water) + CO2 (Fizz).
In other words, you get a dissociated magnesium and citrate molecule, a water molecule and a carbon dioxide molecule.
Defining Dissociation
The definition of dissociation in chemistry is “a general process in which molecules (or ionic compounds such as salts) separate or split into smaller particles such as atoms, ions, or radicals, usually in a reversible manner.”5
This dissociation into smaller parts such as ions is referred to as “ionic,” and it is what makes MAG365 highly bioavailable to the body. Technically we should say that MAG365 is a dissociated magnesium citrate; however, we feel that ionic magnesium citrate is easier to understand.
Whether loose or in a capsule, consuming powdered magnesium citrate – which is in a salt form – requires your stomach acid to “ionise” or activate the magnesium citrate salt into magnesium and citrate ions. This is also known as digestion and it's what your stomach does to absorb all minerals.
Because magnesium citrate is a salt, it doesn’t ionise easily in the body for many of us, which translates to poorer absorption rates. MAG365, on the other hand, is essentially pre-digested in the mug when water is added, as it is already an ionic form.
If you leave MAG365 alone for long enough, the magnesium citrate salt will precipitate out and you will observe a white powder at the bottom of the liquid. At this point, the product is no longer dissociated (ionic) and it has become similar to the aforementioned powders you find in jars or capsules.
Ionic solutions are not always straight forward
While the process seems straight forward, there are many factors to consider. For example, there are variations in magnesium carbonate and citric acid, and using the correct kind in the correct ratio is part of what makes our product unique. Others have tried to emulate MAG365 with little or no success and have ended up with their powder hardening in the jar, having an improper pH balance, or having issues getting it to fizz or taste right without a lot of sweetener and additives. Even a "fizzing" reaction may not guarantee that the end product is an ionic magnesium citrate solution, as there are other ways to get an effervescent reaction.
MAG365 is not the only ionic magnesium on the market, so you have options, but be sure that you know what you are getting. At ITL Health, we make sure all of our products are pure with no fillers or common allergens. This includes sourcing our citric acid from non-GMO sugar beets. Most citric acid comes from corn, which can be a source of digestive sensitivity for many, which is why we don't use corn in any of our products. We also manufacture in small batches to ensure quality control and the right pH balance every time.
Food for Thought
Another form of absorbable magnesium is topical magnesium chloride, which relies on the pH of your skin (~4.9) to dissociate (“ionise”) the magnesium chloride to let it pass through the skin in its ionic form.
ITL Health also manufactures PrizMAG, which is a chelated magnesium supplement in a vegan pullulan capsule. One magnesium molecule is held by two glycine amino acids. The word "chelation" comes from a Greek word meaning “claw,” and one could say it is like two “claws” are holding the magnesium in place.
Our gastrointestinal tract readily absorbs amino acids and will just as easily allow the transport of a magnesium that is attached to these two amino acids. This is why PrizMAG absorbs well even though it is not in an ionic form.
PrizMAG is set apart in the industry as it is one of the only pure magnesium bisglycinate supplements that is free from excipients, stearates and magnesium oxide. Magnesium oxide is a cheaper and smaller molecule that makes a product appear to have a higher magnesium content, but it has a low absorption rate. It's important to be aware of buffered magnesium bisglycinate, as it means it’s mixed with magnesium oxide. (Not all brands disclose that their magnesium is buffered.)
PrizMAG is a comprised of pure magnesium bisglycinate and we can only fit approximately 80mg of elemental magnesium into a single 00 capsule. If another company claims more elemental magnesium in their magnesium bisglycinate capsule, check the label for buffered magnesium (magnesium oxide) or larger capsule sizes. Bisgylcinate and glycinate are used interchangeably.
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References:
- https://www.diffen.com/difference/Covalent_Bonds_vs_Ionic_Bonds
- https://courses.lumenlearning.com/boundless-chemistry/chapter/the-covalent-bond/
- https://en.wikipedia.org/wiki/Organic_compound
- https://en.wikipedia.org/wiki/Salt_(chemistry)
- https://en.wikipedia.org/wiki/Dissociation_(chemistry)
- https://en.wikipedia.org/wiki/Magnesium_citrate
- https://pubchem.ncbi.nlm.nih.gov/compound/Magnesium-citrate-dibasic